[Applying dose banding to the production of antineoplastic drugs: a narrative review of the literature].

نویسندگان

  • Pablo Pérez Huertas
  • Margarita Cueto Sola
  • Paloma Escobar Cava
  • Carmela Borrell García
  • Asunción Albert Marí
  • Eduardo López Briz
  • José Luis Poveda Andrés
چکیده

The dosage of antineoplastic drugs has historically been based on individualized prescription and preparation according to body surface area or patient´s weight. Lack of resources and increased assistance workload in the areas where chemotherapy is made, are leading to the development of new systems to optimize the processing without reducing safety. One of the strategies that has been proposed is the elaboration by dose banding. This new approach standardizes the antineoplastic agents doses by making ranges or bands accepting a percentage of maximum variation. It aims to reduce processing time with the consequent reduction in waiting time for patients; to reduce errors in the manufacturing process and to promote the rational drug use. In conclusion, dose banding is a suitable method for optimizing the development of anticancer drugs, obtaining reductions in oncologic patients waiting time but without actually causing a favorable impact on direct or indirect costs.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Exploring cytotoxic drugs residues in hospital effluents: a narrative review

Background: Cytotoxic waste management is one of the significant issues in healthcare system. The aim of the present study was to review studies conducted on investigation of possible levels of cytotoxic drug residues in hospital effluents. Materials and methods: All peer-reviewed journal articles on investigation of possible levels of cytotoxic drugs residues in hospital effluents which were p...

متن کامل

The Occupational Hazards of Exposure to Antineoplastic and Chemotherapy Drugs in Nurses. A systematic review

Background: By increasing the incidence of cancer, the use of antineoplastic drugs and consequently, oncology nurses’ exposure to the drugs during daily activities has increased. Because of the importance of professional Nurses' health, the purpose of this study is to answer the question of what risks contact with antineoplastic and chemotherapy drugs in nurses?        Method: Studies on the h...

متن کامل

Applicable risk assessment methods in occupational and environmental exposure to nanoparticles - a narrative review

Nanoparticles (NPs) are a heterogeneous group of materials that have various applications, and their risk assessment is an essential condition. This study aimed to review the applicable risk assessment methods in occupational and environmental exposures to NPs. A literature search for articles published since 2005 in Web of Knowledge, Scopus, PubMed, Science Direct, and Google Scholar, using ap...

متن کامل

Biological Monitoring of Healthcare Workers Exposed to Antineoplastic Drugs: Urinary Assessment of Cyclophosphamide and Ifosfamide

Exposure of health care workers to antineoplastic drugs and subsequent adverse health effects is still an open issue. Very little has been studied on the extent of occupational exposure and handling conditions of antineoplastic drugs in Iran. We aimed to determine cyclophosphamide and ifosfamide concentrations in the urine samples of oncology healthcare workers. In addition, we assessed workpla...

متن کامل

The Role of Exercise in Adaptation and Body Response to Doxorubicin-Induced Cellular Toxicity: A Narrative Review Study

Doxorubicin is an anthracycline antibiotic used for the treatment of a wide range of cancers. But unfortunately, due to its accumulation within healthy tissues, DOX treatment results in side effects of cellular toxicity. DOX-induced cellular toxicity occurs as a result of increasing oxidative damage, resulting in apoptosis and cell death. There is currently no standard of care practice to preve...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria

دوره 39 4  شماره 

صفحات  -

تاریخ انتشار 2015